1H-Pyrazole-4-sulfonyl chloride, 1-ethyl-3-methyl- - Names and Identifiers
1H-Pyrazole-4-sulfonyl chloride, 1-ethyl-3-methyl- - Physico-chemical Properties
Molecular Formula | C6H9ClN2O2S
|
Molar Mass | 208.67 |
Storage Condition | Room Temprature |
Sensitive | Irritant |
MDL | MFCD04968671 |
1H-Pyrazole-4-sulfonyl chloride, 1-ethyl-3-methyl- - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Hazard Class | IRRITANT |
1H-Pyrazole-4-sulfonyl chloride, 1-ethyl-3-methyl- - Introduction
1-Ethyl-3-methyl-1H-pyrazole-4-sulfonyl chloride is an organic compound with the chemical formula C7H9ClN2O2S. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: It is a colorless to pale yellow liquid.
-Melting point: about 25°C.
-Boiling point: about 120°C.
-Density: about 1.25 g/ml.
-Solubility: It is soluble in a variety of organic solvents, such as ether, chloroform and dichloromethane.
Use:
1-Ethyl-3-methyl-1H-pyrazole-4-sulfonyl chloride has many applications in the chemical field:
-It can be used as an intermediate for drugs and pesticides, and is used to synthesize a variety of biologically active compounds.
-The compound is also used as a reagent in research and analysis, especially in sulfonylation reactions.
Preparation Method:
A common method for synthesizing 1-ethyl-3-methyl-1H-pyrazole-4-sulfonyl chloride is through the reaction of 1-ethyl-3-methylpyrazole-4-carbonyl chloride and sulfonyl chloride. The specific synthesis method includes the following steps:
1. Add 1-ethyl-3-methylpyrazole-4-carboxylic acid chloride and sulfonyl chloride to the reaction vessel.
2. The reaction mixture is stirred at an appropriate temperature, and the reaction time is usually several hours.
3. The reaction mixture was filtered to give the product of 1-ethyl -3-methyl -1H-pyrazole-4-sulfonyl chloride.
Safety Information:
-Because 1-ethyl-3-methyl-1H-pyrazole-4-sulfonyl chloride is an organic synthesis intermediate, it may be irritating to the skin, eyes and respiratory system and should be handled with caution.
-Wear appropriate protective equipment such as gloves, goggles and face shields when in use.
-During storage and handling, the compound should be stored in a sealed container, avoiding contact with oxygen, water and fire.
-It is recommended to operate in a well-ventilated area to avoid inhaling its vapor or touching liquid. In case of accident or discomfort, seek medical help immediately.
Last Update:2024-04-09 21:04:16